StMU Research Scholars

Featuring Scholarly Research, Writing, and Media at St. Mary's University
April 11, 2026

GPCR Signaling: What is it?

In Cell Biology, there are many pathways within cells that serve different functions. One of these pathways includes GPCR Signaling, or G Protein-Coupled Receptors, which represent the largest and most diverse group of membrane receptors in eukaryotes. They serve as the primary “gatekeepers” of the cell, translating a vast array of external signals including hormones, neurotransmitters, and even light, into specific intracellular responses. This pathway is fundamental to human physiology, regulating everything from your heartbeat and vision to your mood. Because of their critical role in cellular communication and their accessible location on the cell surface, GPCRs are the targets for approximately 34% of all FDA-approved drugs, making them a cornerstone of modern pharmacology and therapeutic intervention.

I’d like to thank professor Dr. Terry Shackleford for her constant feedback in this infographic and providing guidance. I also would like to thank the Department of Biological Sciences and my co-author Illiana Melendez for helping put this infographic together.

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